KMID : 0356620120270010054
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Journal of Korean Society of Endocrinology 2012 Volume.27 No. 1 p.54 ~ p.58
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A Case of Sheehan¡¯s Syndrome with Pancytopenia
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Lee Hyun-Suk
Kwon Byung-Woon Han Jin-Hyung Kim Hee-Jin
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Abstract
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Sheehan¡¯s syndrome is characterized by varying degrees of anterior pituitary dysfunction due to postpartum ischemic necrosis of the pituitary gland after massive bleeding. The spectrum of clinical presentation of Sheehan¡¯s syndrome is broad, with changes from nonspecific complaints, such as weakness, fatigue, and anemia, to severe pituitary insufficiency resulting in coma and death. Normochromic anemia is commonly associated with Sheehan¡¯s syndrome, but pancytopenia is rarely observed in patients with Sheehan¡¯s syndrome. We describe a 57-year-old woman with Sheehan¡¯s syndrome who presented with pancytopenia that was treated by hormone replacement with levothyroxine and glucocorticoid.
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KEYWORD
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Glucocorticoids, Hypopituitarism, Pancytopenia, Thyroxine
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